Voorjaarsvergadering NVU, 11 en 12 mei 2017, ’s-Hertogenbosch

6β,8β-Dihy­droxy­eremophil-7(11)-en-8α,12-olide

The title compound, C(15)H(22)O(4), an eremophilane sesquiternoid, was isolated from the roots of Ligularia virgaurea. Both six-membered rings (A and B) adopt chair conformations and the five-membered ring is almost planar (r.m.s. deviation = 0.016 Å). The two methyl and two hy-droxy groups adopt a syn conformation and the A/B ring junction is cis-fused. An intra-molecular O-H⋯O hydrogen bond g...

6β-Hy­droxy­eremophil-7(11)-en-8β,12-olide

The title eremophilenolide, C(15)H(22)O(3), is a natural compound isolated from Senecio laetus Edgew. The two cis-fused six-membered rings have chair confomations and the five-membered ring has a planar envelope conformation [maximum deviation = 0.010 (1) Å]. The β-hy-droxy group participates in inter-molecular O-H⋯O hydrogen bonding, forming mol-ecular chains along the a axis.

of the Month , 12 / 2017 ( Mizrahi ' s lab )

of the Month , 12 / 2017 ( Sompolinsky ' s lab )

of the Month , 12 / 2017 ( Loewenstein ' s lab )